n South African Medical Journal - The role of the state in establishing a public cord blood stem cell bank : editorials

Volume 100, Issue 5
  • ISSN : 0256-9574
  • E-ISSN: 2078-5135



Allogeneic stem cell transplantation has become a curative treatment option for many patients with haematological malignancies, bone marrow failure syndromes, thalassaemia, sickle-cell disease and some rare disorders of the blood and bone marrow. Ideally, stem cells from the peripheral blood or bone marrow are sourced from sibling donors or from a matched unrelated donor if a sibling donor is not available. Alternatively, stem cells may be obtained from umbilical cord blood (UCB). The advantages of the latter over conventional sources of stem cells include that tissue matching requirements are less stringent, healthy donors are not exposed to invasive procedures, and transplants can be performed without delay.

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