n South African Medical Journal - South African ischaemic stroke guideline, 2010 : correspondence
|Article Title||South African ischaemic stroke guideline, 2010 : correspondence|
|© Publisher:||Health and Medical Publishing Group (HMPG)|
|Journal||South African Medical Journal|
|Author||Sa'ad Lahri and Lee Wallis|
|Publication Date||Jan 2011|
|Pages||7 - 8|
|Keyword(s)||Stellenbosch University and University of Cape Town|
To the Editor: We believe the guideline by Bryer et al. to be overdue and well constructed, and generally to contain excellent recommendations. However, the authors note that intravenous tissue plasminogen activator (tPA) 'is an accepted therapy' and 'significantly improves outcome'; particular reference is made to the ECASS III trial to justify its use within 4.5 hours of stroke onset. We believe that this is a dangerous and unsupported recommendation.
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