n South African Medical Journal - A historical review of XDR tuberculosis in the Western Cape province of South Africa : scientific letter
|Article Title||A historical review of XDR tuberculosis in the Western Cape province of South Africa : scientific letter|
|© Publisher:||Health and Medical Publishing Group (HMPG)|
|Journal||South African Medical Journal|
|Affiliations||1 University of Cape Town, 2 University of Cape Town, 3 University of Cape Town, 4 University of Cape Town, 5 University of Cape Town, 6 University of Cape Town, 7 University of Cape Town and 8 University of Cape Town|
|Publication Date||Sep 2011|
|Pages||636 - 638|
There are limited data on the temporal relationship between the regional introduction of multidrug-resistant tuberculosis (MDRTB) treatment and the subsequent development of extensively drug-resistant TB (XDR-TB). The first XDR-TB case in the Western Cape province of South Africa was recorded in 1992, approximately 5 - 7 years after the regional introduction of MDR-TB-like treatment. Between 1990 and 2002 we identified 48 patients with XDR-TB in the Cape Metropole region of the Western Cape province. Patients were predominantly HIV-uninfected and median survival was 10.8 months. XDR-TB has therefore been present in the Western Cape at least since 1992. These data inform public health policy relevant to the introduction of new anti-TB drug regimens.
Article metrics loading...