n South African Medical Journal - Phased implementation of screening for cryptococcal disease in South Africa : editorial

Volume 102, Issue 12
  • ISSN : 0256-9574
  • E-ISSN: 2078-5135



is the most common cause of laboratory-confirmed meningitis in South Africa. Despite the increased coverage of antiretroviral treatment (ART), the country's incidence of cryptococcal meningitis remains high, and in routine care settings, the disease has a case-fatality ratio of >50% at 12 weeks post-diagnosis. Screening and pre-emptive antifungal treatment is desirable to prevent the development of cryptococcal meningitis and associated deaths.

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