n South African Medical Journal - Progress of preventing mother-to-child transmission of HIV at primary healthcare facilities and district hospitals in three South African provinces : scientific letters
|Article Title||Progress of preventing mother-to-child transmission of HIV at primary healthcare facilities and district hospitals in three South African provinces : scientific letters|
|© Publisher:||Health and Medical Publishing Group (HMPG)|
|Journal||South African Medical Journal|
|Affiliations||1 Kheth'Impilo AIDS free living, 2 Kheth'Impilo AIDS free living, 3 Kheth'Impilo AIDS free living, 4 Red Cross War Memorial Children's Hospital, 5 University of Cape Town and 6 University of the Western Cape|
|Publication Date||Feb 2012|
|Pages||81 - 83|
Improving national prevention of mother-to-child transmission (PMTCT) services in South Africa has been challenging. PMTCT outcomes were analysed at 58 primary- and secondary-level antenatal facilities across seven high HIV burden sub-districts in three provinces, over an 18-month period during which new South African PMTCT clinical guidelines were implemented and a nurse quality mentor programme was expanded. Early infant HIV DNA polymerase chain reaction test positivity reduced by 75.2% from 9.7% (95% confidence interval (CI) 8.1 - 11.5%) to 2.4% (95% CI 1.9 - 3.1%) (p<0.0005). HIV test positivity at 18 months of age decreased by 64.5% from 10.7% (95% CI 7.2 - 15.1%) to 3.8% (95% CI 2.4 - 5.6%) (p<0.0005). PMTCT outcomes have improved substantially at these facilities.
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