n South African Medical Journal - Tricyclic antidepressant overdose necessitating ICU admission : research
|Article Title||Tricyclic antidepressant overdose necessitating ICU admission : research|
|© Publisher:||Health and Medical Publishing Group (HMPG)|
|Journal||South African Medical Journal|
|Affiliations||1 Stellenbosch University, 2 Stellenbosch University, 3 Stellenbosch University, 4 Tygerberg Academic Hospital, 5 Tygerberg Academic Hospital and 6 Tygerberg Academic Hospital|
|Publication Date||May 2012|
|Pages||293 - 294|
Tricyclic antidepressant (TCA) overdose necessitating intensive care unit (ICU) admission remains a significant problem in the Western Cape. In this retrospective study, we reviewed the course of life-threatening TCA overdose in our centre to identify potential prognostic indicators. TCA levels >1 000 ng/ml were associated with QT and QRS prolongation and convulsions. However, no single parameter predicted non-survival. The overall mortality of TCA overdose was very low. Our findings should encourage clinicians to offer medical care including ICU admission, if necessary, to patients with TCA overdose.
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