n South African Medical Journal - Prevention of infective endocarditis in developing countries - justifiable caution? : forum - issues in medicine
|Article Title||Prevention of infective endocarditis in developing countries - justifiable caution? : forum - issues in medicine|
|© Publisher:||Health and Medical Publishing Group (HMPG)|
|Journal||South African Medical Journal|
|Affiliations||1 Walter Sisulu University, 2 East London Hospital Complex and 3 University of KwaZulu-Natal|
|Publication Date||Aug 2012|
|Pages||652 - 654|
The internationally accepted practice of prescribing prophylactic antibiotics to individuals at risk of infective endocarditis has come under scrutiny. There are no published high-quality randomised controlled trials of the intervention, but new insights have emerged. Bacteraemic episodes are common following simple activities such as brushing teeth. Endocarditis following procedures is extremely rare, and systematic reviews of the evidence for prophylactic antibiotics have failed to demonstrate efficacy.
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