n South African Medical Journal - Charting a path along the continuum of PMTCT of HIV-1, to elimination, and finally to eradication : editorial

Volume 104, Issue 1
  • ISSN : 0256-9574
  • E-ISSN: 2078-5135



In this editorial we traverse the continuum of transmission of HIV-1 from mothers to children to highlight the biomedical history of this problem. Treatment has progressed from prevention with antiretrovirals (ARVs) through to a broader set of interventions, including various breastfeeding options and other health system improvements, that have increased the possibility of eliminating mother-to-child-transmission (MTCT) of HIV. At the far end of the continuum, the spectacular findings in the case of the Mississippi 'cured' baby indicate that eradication is possible.

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