n South African Medical Journal - Management challenges in tuberculosis and HIV : CME - guest editorial

Volume 104, Issue 12
  • ISSN : 0256-9574
  • E-ISSN: 2078-5135



Globally, South Africa (SA) is disproportionately affected by the epidemics of tuberculosis (TB) and the human immunodeficiency virus-1 (HIV-1). The intersection of these two diseases has resulted in an unprecedented disease burden. It is estimated that 12.2% of South Africans are HIV-infected - a total of 6.4 million people, the largest number in any country in the world. SA has the second highest annual incidence of TB after Swaziland - approximately 1% of the population develop active TB disease each year (an estimated 530 000 people in 2012). While SA comprises 0.7% of the world's population, it is estimated that of all cases of HIV-associated TB that occur worldwide annually, 30% are in SA.

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