n South African Medical Journal - GeneXpert TB 8 : a point-of-care diagnostic pilot : correspondence

Volume 104, Issue 8
  • ISSN : 0256-9574
  • E-ISSN: 2078-5135



The point-of-care (POC) GeneXpert MTB/RIF detects (MTB) and drug resistance in under 2 hours and was hailed a 'game-changer' for tuberculosis (TB) control. Recent results from Evaluating a New Diagnostic Trial (EXTEND) show that while implementing the GeneXpert had more confirmations of TB than sputum microscopy, levels of loss to follow-up and mortality were not reduced in the GeneXpert group. These results are discouraging. However, GeneXpert was not used as a true POC service. Using the diagnostic at POC, where results are handed to patients at the time and place of sample collection, may yield different outcomes.

Loading full text...

Full text loading...


Article metrics loading...


This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error