n South African Medical Journal - The utility of urine sulphosalicylic acid testing in the detection of non-albumin proteinuria : continuing medical education - case report

Volume 105, Issue 2
  • ISSN : 0256-9574
  • E-ISSN: 2078-5135



We report two cases of immunoglobulin light chain proteinuria (Bence Jones proteinuria) detected by simple side-room investigations: urine dipstick negative/1+, but with strong positive precipitation on addition of an equal volume of sulphosalicylic acid (SSA) 3%. We highlight a significant limitation of urine dipstick testing, namely specificity for albumin, and the utility of SSA testing for the detection of urinary free light chain immunoglobulins.

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