n South African Medical Journal - Outcomes in treatment with darunavir/ritonavir in ART-experienced paediatric patients : correspondence

Volume 105, Issue 5
  • ISSN : 0256-9574
  • E-ISSN: 2078-5135



To the Editor: Increasing development of resistant mutations to first- and second-line antiretroviral (ART) regimens among children is a matter of concern, as limited third-line paediatric ART preparations are available in the public sector. There are various explanations for this increase, including drug interactions leading to reduced bioavailability as seen in tuberculosis (TB) co-infection.

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