n South African Medical Journal - Is South Africa at risk for Zika virus disease? : editorial
|Article Title||Is South Africa at risk for Zika virus disease? : editorial|
|© Publisher:||Health and Medical Publishing Group (HMPG)|
|Journal||South African Medical Journal|
|Affiliations||1 National Institute for Communicable Diseases, 2 National Institute for Communicable Diseases and 3 National Institute for Communicable Diseases|
|Publication Date||Mar 2016|
|Pages||232 - 233|
Zika virus (ZIKV) was originally isolated from a sentinel rhesus monkey in the Zika forest in Uganda in 1947. Twenty-one years later the virus was isolated for the first time from naturally infected humans in Nigeria. ZIKV belongs to the genus Flavivirus, family Flaviviridae, comprising enveloped viruses with RNA genomes, mostly arthropod borne. For decades ZIKV remained relatively unknown, affecting mainly monkeys and occasionally causing a mild disease in humans residing across a narrow equatorial belt in Africa and Asia. The virus is transmitted to humans by daytime active Aedes aegypti mosquitoes and usually causes a self-limiting, non-fatal febrile infection characterised by a maculopapular rash, arthralgia, conjunctivitis, myalgia and headache.
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