Sea-water enemas were given daily to three fasting volunteers deprived of all fluid for a period of eighty hours; three similar volunteers, also fasting and deprived of all fluids, served as controls. It is our opinion that sea-water, although absorbed from the rectum, is of little or no value in maintaining the body's waterbalance, and is possibly even harmful in that it enforces tissue dehydration and causes the kidney maximal work, as shown by the lumbar pain in two of the three sea-water group.
A rare case of microcephaly in a newborn infant combined with a severe congenital deformity of the nervous system, amounting to an almost total absence of the brain, is decribed. The skull of this abnormal case showed an advanced type of microcephaly, and a comparison is made between previously reported cases of microcephaly in adults and the present infantile example.
The development of anthrax in guinea-pigs could be inhibited if sulphapyridine was given by mouth an hour after infection. Sulphapyridine by the mouth could modify, but not cure, anthrax if treatment was delayed.