oa South African Medical Journal - The treatment of vomiting of pregnancy by drugs which stimulate the para-sympathetic nervous system*

Volume 17, Issue 18
  • ISSN : 0256-9574
  • E-ISSN: 2078-5135



*This article has been published with the kind permission of A. Paton Martin, M.D., O.B.E., Director of Medical Services, Southern Rhodesia, and Wing-Commander J.B. Wallace, M.D., Principal medical officer, Rhodesian Air Training Group, Southern Rhodesia. Cases of the vomiting of pregnancy, treated with eserine sulphate, are discussed. The treatment is descriptionbed. It is suggested that cases of the vomiting of pregnancy are in a state of hypertonus of the sympathetic nervous system, and that this is concerned in the etiology of the disease. Evidence is given to support this hypothesis. Some of the actions of drugs which stimulate the parasympathetic nervous system are given. It is suggested that eserine sulphate, being one of these drugs, should diminish a state of sympathicotonia. It is thought that sympathicotonia plays a similar role in eclampsia, hypertention and albuminuria. Evidence is given to justify this supposition and warrant further investigation into the influence of the autonomic nervous system on the toxaemia, of pregnancy.

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