The differential diagnosis of hypothyroidism has been discussed. The use of thyrotrophic hormone injections as an aid to diagnosis has been suggested. The clinical, metabolic and chemical changes, notably the occurrence of creatinuria, have been descriptionbed after the injections of thyrotrophic hormone in normaland hypothyroid subjects.
The use of C10 in a varied series of cases is descriptionbed. Whereas adequate abdominal muscular relaxation was obtained, the effect on the muscles of respiration was, by comparison, negligible. The brief action of the drug is an advantage. C10 was found to be a safe relaxing agent and in no case were there any significant side-effects. On no occasion was it necessary to use the antidote Cs (antilusin).