oa South African Medical Journal - Rh incompatibility : an analysis of 1,320 investigations
The information to be derived from the above analysis may be summarized as follows: the imperative need for the systematic Rh testing of all females, especially during the ante-natal period, is once more amply demonstrated. Rhesus factor incompatibility is unimportant as an aetiological factor in repeated abortions during the early months of pregnancy. A proportion of the foetal deaths and deaths at term can be avoided if steps are taken to diagnose sensitization of the mother during pregnancy. Such information also permits prompt treatment of affected babies with a corresponding improvement in prognosis. The danger of transfusing females of unknown Rh status is illustrated and emphasized. Of 59 affected babies, 16 survived without transfusion; 35 were transfused with Rh negative blood and25 of these babies survived. The recovery rate of 70% compares very favourably with figures published overseas and further improvement is to be anticipated.
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