oa South African Medical Journal - Allergic and vasomotor rhinitis : treatment with anthisan (neoantergan) : report on 36 cases
Thirty-six cases of nasal allergy were treated with anthisan; 70%, by adjustment of dosage, were given complete subjective relief so long as they continued to take the original minimal effective controlling dose. This figure is in accord with the results published by Feinberg et al. (1947) using benadryl and neoantergan, and by Calder (1948) using anthisan. There is no evidence that when the drug has been taken for a long time, the effective dose gradually becomes smaller, nor is there any evidence of increasing tolerance. There has been nothing in this series of cases to suggest that the long-continued exhibition of the drug over months produces any ill-effects.
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