Penicillin alone and sulphasuxidine alone are in a high proportion of cases capable of ' success' in the treatment of acute ulcerative amoebic dysentery. Simultaneous use of the two drugs results in a greater proportion of cures. The danger of masking the diagnosis of amoebiasis by the indiscriminate use of sulphonamides is stressed. It is suggested that the anti-bacterial drugs exhibit their anti-amoebic action by the destruction of organisms symbiotic to the amoeba.
The results obtained in treating 365 cases of early syphilis with a treatment schedule entailing the administration of penicillin, arsenic and bismuth of a 7 1/2-8 day period, are put forward. Only a small number, 86 (23.56%) of the original 365 cases continued to attend for a 12-month period. Of this number 12 (13.95%) were treatment failures. There were no serious reactions observed in any of the patients who were all admitted to hospital for treatment. Seventy-six (20.82 %) of the original 365 cases had a complete spinal fluid examination at the sixth month after the completion of treatment. In one of these only was a doubtful reaction observed in the Wassermann tests, all other tests being normal. The schedule tested cannot be regarded as giving very satisfactory results in view of the considerable number of treatment failures in secondary syphilis. The results emphasize once more the favourable outcome in early primary syphilis compared with that obtained in later cases.
A battery of liver function tests was run on 27 tuberculous patients grouped into severe, moderate and mild categories. Hepatic dysfunction was found in a large proportion of the cases of severe pulmonary tuberculosis studied. The best correlation was found between the thymol turbidity test, the cephalin cholesterol flocculation test and the bromsulphalein excretion test using the 5 mg. per kilogram of body weight dose. Statistical analysis of the overall results show no significant figures.