A review of the available literature shows that only five cases of hyperthyroidism, occurring in the first year of life, have been reported. One of these cases, born of a woman suffering from thyrotoxicosis, presented signs at birth. A further case is reported of a baby, born while the mother was suffering from poorly controlled Graves' disease, developing signs of hyperthyroidism towards the end of the first week of life. As far as could be determined the condition appeared to be self-limiting and, with supportive therapy, the baby made a complete recovery. Attention is drawn to similarities and differences in the six reported cases and a short discussion follows on the possible aetiology of the condition.
Three cases of idiopathic gangrene of the scrotum are presented. The clinical and pathological features of the disease in each case conform to the original descriptionption of the condition as given by Fournier in 1894. No demonstrable cause of the gangrene could be found in any of the cases. A short review of the literature is given.