The case is presented of a Cape Coloured female of 17 years in whom congenital cystic dilatation of the common bile duct was an incidental finding at autopsy. It is believed that this is the first case in which accessory ducts, communicating with the cyst, have been descriptionbed. A suggestion is made about the possible mode of origin of these ducts. The literature, especially with regard to cases manifesting during pregnancy, is discussed briefly, and the current view on aetiology and pathogenesis summarized.
Standard doses of I gm. of ferrous sulphate were given by mouth to 5 normal controls and to 8 pregnant women and the increase in serum iron over the next six hours was determined. It is found that in pregnancy the curve of serum iron rises faster and further and drops more steeply than in the non-pregnant controls. Intravenous administration of simple rapidly ionizable iron salts show a similar phenomenon. Curves from four pregnant cases and from five controls are presented. When complex saccharated iron compounds are given the elemental iron is slowly liberated so that serum iron determinations include measurements of iron not combined to serum proteins. Urinary excretion of iron was investigated in these cases and it is shown that, although the concentration of iron in the urine is increased, the total iron lost by this route is not significant. It is concluded that the pregnant woman has an enhanced power to absorb and transport iron and it is argued that this constitutes further evidence in support of the thesis that a state of latent iron deficiency exists In pregnancy.
A case of acute idiopathic aplastic anaemia of pregnancy is reported in a primigravida, aged 28 years. Repeated blood transfusions were necessary to maintain life during pregnancy. Complete and rapid recovery took place after the termination of pregnancy at the 36th week.