oa South African Medical Journal - The cardiac action of the antihistamine compounds : a review of the literature and a preliminary case report

Volume 26, Issue 30
  • ISSN : 0256-9574
  • E-ISSN: 2078-5135



A brief review of the literature on the cardiac action of the antihistamine compounds is presented. Their action on the heart is compared with that of quinidine. A preliminary report of case with frequent ventricular ectopic beats, in which substances with a quinidine-like action were used, is presented. It is suggested that the antihistamine compounds be given a further more extensive and carefully controlled clinical trial in cardiac arrhythmias.

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