oa South African Medical Journal - A report on succinylcholine chloride (scoline) : an ultra-short-acting muscle relaxant



The use of Scoline in a series of about 100 cases is descriptionbed. It has been found to be a valuable drug giving a short period of profound relaxation lasting as a rule between 3 to 5 minutes, and during which intubation may be performed with ease. Its use in such short cases as tonsillectomy, dental work, bronchoscopy and oesophagoscopy is descriptionbed. The method used was to give twice the sleep dose of Thiopentone followed immediately by the Scoline through a 3-way tap. After inflation of the lungs with oxygen the patient is intubated and ether is introduced rapidly by manual compression of the bag (except in the case of bronchoscopy, where further doses of Thiopentone and Scoline are given). It has been found to be the relaxant of choice in electro-convulsive therapy. Smaller doses of Thiopentone and Scoline are given. Means by which the patient may be inflated with oxygen must always be at hand.


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