oa South African Medical Journal - Active tuberculosis : the Middlebrook-Dubos haemagglutination test in its diagnosis



I. Of 91 cases of active tuberculosis 50 yielded haemagglutination titres of I: 16-1 : 128, 14 gave a titre of 1: 8, and the remaining 30 yielded titres of 0-1: 4. 2. Of 119 normal persons, 101 yielded titres of 0-1 :4,14 gave a titre of I: 8, 3 a titre of I: 32, and I a titre of 1: 128. 3. It would appear that a positive haemagglutination result (a titre above I: 8) is significant, and a titre of 1: 8 or below may occur in a high percentage of cases of active tuberculosis. 4. There appears to be little correlation between the erythrocyte sedimentation rate (Wintrobe) and the haemagglutination titre in individual cases of active tuberculosis. Work is in progress on the correlation of the haemagglutination titre and erythrocyte sedimentation rate in cases under treatment.


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