oa South African Medical Journal - Two cases of an unusual form of pneumonia

Volume 26, Issue 48
  • ISSN : 0256-9574
  • E-ISSN: 2078-5135



Two fatal cases of an unusual pneumonia are descriptionbed. Following an acute respiratory infection resembling influenza, both these patients developed a long progressive illness characterized by cough, haemoptysis, progressive dyspnoea, cyanosis and terminal asphyxia. Serial X-rays revealed a progressive march of a patchy consolidation commencing in the bases and proceeding towards the apices of the lungs. The direct Coombs test for sensitization of the red blood cells was postive in both cases. Postmortem examination revealed firm fleshy lungs with extensive consolidation. Microscopic examination showed stripping of the lining cells of the alveoli, and abundant hyaline fibrin in the alveoli associated with a mononuclear infiltration but with few neutrophil leucocytes. The aetiology of the condition was not determined but it is suggested that it may have been due to an auto-allergic state initiated by an acute respiratory infection.

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