oa South African Medical Journal - The treatment of syphilis in pregnancy : using procaine penicillin with aluminium monostearate only

Volume 26, Issue 52
  • ISSN : 0256-9574
  • E-ISSN: 2078-5135



The results of treating 169 pregnant, presumably syphilitic, women with 4.8 million units of penicillin in the form of the procaine salt suspended in oil and combined with % aluminium monostearate, are given. In only 55 of the 170 children born to these mothers was the final status decided; the rest were defaulters. Two of the infants are considered failures though none of the mothers received any anti-syphilitic treatment until the last trimester of pregnancy. Forty-seven infants were examined clinically and serologically at the third month. All were free from syphilis. The fact that only 12 mothers showed signs of early syphilis detracts from the value of this report, though good grounds exist for believing in the efficacy of the schedule employed. Some observations on the Wassermann test are added.

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