The case presented is one of uterine fibroids found, at operation, to have migrated into the left ischio-rectal fossa. It was thought to be of interest because a review of the literature failed to disclose any similar case. It was further remarkable in that a fibroid mass of such size could be so successfully 'hidden' as to be missed completely on clinical examination. The anatomy of the case is illustrated with the aid of a diagram.
Some of the difficulties inherent in studying the incidence of cancer among primitive peoples are outlined. Methods are descriptionbed which will probably assess some of these difficulties. It is unlikely that very accurate statistics on cancer can be obtained in the Bantu, but only a good estimate. It is hoped to obtain such an estimate by a survey organized by the South African Institute for Medical Research with assistance from the National Cancer Institute of America. The use of proportional rates is discussed and their strict limitation emphasized. Information obtained by the use of proportional rates at Baragwanath non-European Hospital is summarized. The unique position of South Africa for cancer demographic studies is stressed.
1. Amyoplasia congenita, also known by a variety of other names, is a congenital disease. It is characterized by deformities of joints and muscles, usually accompanied by other defects a lso of congenital origin. 2. A typical case is presented and a suggestion made about the causation of the fractures sustained during birth. A second case, which appears to be an example of the same condition, is also reported. 3. A survey of the available literature is made to show the clinical features and pathology of the disease. 4. The mental state is considered, as is the prognosis and treatment. 5. The pathology of the joint and muscle lesions seems to be well understood and it has been suggested that there is a fairly close relationship between amyoplasia congenita and the spinal muscular atrophies of Oppenbeim and Werdnig Hoffmann. Unanimous agreement has not yet been reached whether amyoplasia congenita is, in fact, primarily a disease of the nervous system rather than a primary muscular condition.