A brief review has been given of the literature concerning the psychosomatic aspects of ulcerative colitis, together with case reports of 5 patients treated by psychotherapy. The findings insofar as personality traits, precipitating factors and the relationship of the course of the disease to life situations, bear a marked similarity to the conclusions of previous studies. The success of psychotherapy in certain cases would seem to confirm the need for further work in this field, particularly in the early stage of the disease.
In January and February, the late summer of 1952, an epidemic of an illness characterized by signs and symptoms of Bornholm disease or pleurodynia affected the children of a school hostel in Middelburg, Transvaal. The illness was sudden in onset in most cases with acute epigastric pain and tenderness often associated with severe headache, nausea, vomiting and fever. The fever lasted 1-3 days. In one third of the cases the illness relapsed with a recrudescence of the signs and symptoms, and in one tenth of the cases a second relapse occurred. In children the abdominal signs and symptoms were most obvious. In 5 adult cases chest signs and symptoms were more prominent. In a laboratory study it was shown that this illness was associated with an infection of a Coxsackie group B type 4 virus. In addition to being pathogenic to and producing characteristic lesions in baby mice, this virus was also pathogenic to adult mice, causing in some an extensive destruction and inflammation of the pancreas. The possibility of involvement of the pancreas in human cases is mooted, but no studies of this possibility were made in this outbreak. It is now becoming clear that outbreaks of Bornholm disease are caused by infection with Coxsackie virus, particularly by strains of the B group. This view has received further support from the results of this study.
The post-operative radiological features in a case of circumferential prolapse of gastric mucosa into the duodenum are here descriptionbed for the first time, as far as we are aware. During 2 examinations, carried out 18 months after the operation, the bulb never exhibited the umbrella-like appearance seen pre-operatively; in the majority of views the bulb appeared quite normal, in some there was a small filling defect on the greater curvature side of the base. This indicates that a certain degree of prolapse is still present, but that the volume of prolapsing mucosa has been greatly reduced. The filling defect only appeared during contraction of the 'canalis egestorius' or, in other words, during antral systole. The symptoms have not recurred.
1. Two cases of children presenting with frequent petit mal attacks which proved resistant to well-known anti-convulsant drugs, were put on ACTH, 5 mg. 6- hourly, or 10 mg. 3 times per day, gradually reducing the dosage. 2. Improvement was dramatic and maintained, the children remaining well until the present. 3. ACTH is presumed to work on the basis of an autoantigen- antibody reaction in disea ed brain tissue, or else as directly affecting epileptogenic foci, biochemically.