oa South African Medical Journal - The cause of essential hypertension*



A paper read to the Physician's Group of the Southern Transvaal Branch of the Medical Association of South Africa on 3 July 1952. 1. The mechanism of blood pressure elevation in response to emotional stress is descriptionbed. 2. Evidence is adduced to show that in the regulation of the blood pressure, the adrenal medulla and the thyroid gland have antagonistic actions. 3. Essential hypertension is defined as a disorder in which the normal blood-pressure-raising mechanism is not countered or is inadequately countered by the thyroid gland. Thyroid insufficiency, absolute or relative is the basic factor in the problem of causation. I would like to thank Winthrop Products (pty.) Ltd., for supplies of I-noradrenaline (Levophed) and at the same time to express my gratitude to those who volunteered for the experiments.


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