(1) Five cases of post-partum megaloblastic anaemia in Africans are descriptionbed. (2) Diagnosis was confirmed by sternal marrow biopsy. (3) There was no tendency for spontaneous remission. (4) Four of the cases successfully breast-fed their infants Although the mothers were severely anaemic. (5) Response to therapy varied. (6) All the cases were diagnosed 3 months after the Birth of their infants.