oa South African Medical Journal - Sarkoied van Boeck behandel met kortisoon

Volume 27, Issue 37
  • ISSN : 0256-9574
  • E-ISSN: 2078-5135



A case of Boeck's sarcoidosis is descriptionbed in a white South African male. The patient had suffered from a chronic lung affection for the past 10 years and for 5 years before admission to hospital he complained of generalized glandular enlargement, dysphagia, loss of weight and general malaise. On examination there were atrophic skin lesions on the forehead and neck and considerable enlargement �of the axillary and inguinal glands. Radiograms of the lungs showed widespread bilateral fibrotic changes together with enlargement of the hilar glands. Swallowed barium showed a partial obstruction of the oesophagus due to pressure by the mass of hilar glands. Histological examination of a lymph node and of a skin lesion revealed the epithelioid follicles and giant cells of sarcoidosis. Treatment with cortisone caused a marked diminution in size of the enlarged glands and skin lesions within 2 weeks. There was also a well-marked improvement in the patient's general"" condition and, although no radiological improvement in the lung lesions could be demonstrated, his maximal breathing capacity showed a distinct increase.

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