oa South African Medical Journal - Osseous changes in neural leprosy*
*A paper read at the South African Medical Congress, Johannesburg, September 1952. Bone atrophy in neural leprosy has never been adequately explained. The results of our investigations have shown that there are three essential features in neural leprosy which accord to a significant degree with each other: the degree of peripheral nerve damage as evidenced by extent of anaesthesia, failure of reflex vasomotor responses and bone atrophy. It is suggested that this failure of reflex vasomotor response which is due to destruction of vasomotor fibres by the leprous peripheral neuritis is of fundamental importance in the causation of the osseous changes.
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