oa South African Medical Journal - Treatment of non-specific urethritis with penicillin



1. Eighty-five males with uncomplicated non-specific urethritis were treated with a minimal dose of 3 daily injections of 600,000 units of procaine penicillin with aluminium monostearate, or its equivalent, with 36 treatment failures within 3 post-treatment months. 2. The failure rate was significantly higher in those who had previously received streptomycin or sulphonamides than in those who were previously untreated. 3. Penicillin is considered on a par with sulphadiazine, and neither drug is considered satisfactory for the routine treatment of non-specific urethritis.


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