The indications for the surgical correction of mitral stenosis are reviewed. The majority of cases with this condition have a poor prognosis once disability commences, and valvotomy should be considered whilst the patient is still in the ideal stage and before complicating features develop. The effect of these features on operability is discussed. It is pointed out that although the mortality and prognosis is less favourable in cases with complications, few of them prohibit operation, and that in the majority good results usually follow a successful valvotomy. In most cases the decision on operation can be made from a consideration of the patient's history and the findings of routine physical, electrocardiographic and radiological examination.
1. Four cases of fibrocystic disease of the pancreas are descriptionbed to illustrate the ways in which the disease may present and to show that more than one member of a family may be affected. 2. Reports from the literature indicate that the condition is transmitted as a simple recessive trait. 3. Points in the diagnosis and treatment are discussed and reference is made to a method which attempts to liquefy the tenacious mucus in the respiratory tract. 4. Cor pulmonale is mentioned as an additional complication.