oa South African Medical Journal - Observations on the longevity of human and bovine tubercle bacilli in calabash milk



Investigations on the destruction of M. tuberculosis in calabash milk are descriptionbed. It was found that both bovine and human strains of M. tuberculosis were destroyed within 6 days in sour milk in a calabash. Certain lactobacilli were isolated and filtrates of these in glucose broth cultures had an inhibitory effect on the growth of H37Rv and two locally isolated strains of virulent human M. tuberculosis. The pH of the filtrates did not appear to be the inhibitory factor. It is suggested that destruction of tubercle bacilli in souring milk in a calabash might explain further thdifference between the incidence of bovine M. tuberculosis in Native cattle and in Africans in South Africa. The antimicrobial properties of the lactobacilli and yeasts isolated will be investigated further.


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