oa South African Medical Journal - Christmas disease* : report on a case

Volume 28, Issue 5
  • ISSN : 0256-9574
  • E-ISSN: 2078-5135



*Paper read at the first conference of the South African Paediatric Association held at Durban 21 August 1953. The prolonged recalcification time and the prothrombin consumption test put this case into the haemophilic and 'haemophilic-like' group of haemorrhagic diatheses. The defect in the case has been corrected by the addition of haemophilic plasma and by a normal control. In addition, the addition of plasma from a case of 'Christmas Factor' has failed to correct the defect. This would imply that this is not a case ofhaemophilia, but that the defect in this case is Factor VII or the associated so-called Christmas Factor.

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