oa South African Medical Journal - The physiological aspects of gastric ulcer

Volume 3, Issue 21
  • ISSN : 0256-9574
  • E-ISSN: 2078-5135



Ulceration occurs most frequently in portions of the stomach where acid-secreting cells do not exist, and where movement is most marked; to a less extent in the portion where acid secretion is most intense. A possible contributing cause is the under-production of anti-enzyme at certain points, which, in the case of persistent hyperacidity, may give rise to ulceration.

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