oa South African Medical Journal - Auto-immune response to lens and uveal protein

Volume 38, Issue 7
  • ISSN : 0256-9574
  • E-ISSN: 2078-5135



There is substantial evidence that cases of lens-induced uveitis show hypersensitivity to lens protein and that this hypersensitive state can be transferred to an experimental animal; also that lens protein in the presence of adjuvant is capable of inciting an auto-immune reaction in the guinea-pig, similar histologically to endophthalmitis phacoanaphylactica in man.

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