oa South African Medical Journal - The cause of the myocardial 'hyaline degenration' induced in rats fed predominantly maize diets supplemented with either the NNRI food formulae or skimmed-milk powder



In an experiment with 5 groups of young rats, each group receiving a basal diet of cooked and dried maize meal plus NNRI Food Formula V and certain supplements for 140 days, it was found that: the basal diet plus coconut oil induced hyaline degeneration in myocardium and skeletal muscle; the incidence rating of the hyaline degeneration was raised to 100% and the degree of tissue change was enhanced by supplementation of the basal diet with cod-liver oil; supplementation of the basal diet with vitamin E afforded complete protection against hyalinization; and supplementation with selenium and anti-oxidants afforded only a limited degree of protection against the muscular tissue changes.


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