Apparently abnormal blood chemistry results may be caused by many factors other than disease. Incorrect specimen collection with excessive venous stasis and haemolysis, or undue delay in separating cells from serum can affect a number of tests. Medication may also influence results, notably the protein-bound iodine, as may procedures such as rectal examination and intravenous fluid administration.
A study was undertaken to assess the accuracy of a new Dextrostix/Reflectance Meter system for rapid blood glucose determinations over a wide range of values, in 390 consecutive patients attending a busy diabetic clinic.
Sera from 97% of 200 patients with invasive amoebiasis and 15% of 100 general medical patients gave positive results when quantitatively tested with a latex agglutination test All degrees of agglutination were observed and no correlation was found between latex agglutination results and non-invasive amoebae in the gut.