oa South African Medical Journal - The possible central stimulant mechanisms of some appetite suppressants



The probable mechanisms involved in the central stimulating action, as measured by an increase ion locomotor activity of animals, were investigated for a number of phenylethylamine derivatives. Amphetamine, methylamphetamine, propylhexedrine, phentermine, mephentermine and p-chloroamphetamine probably produce their stimulant action by a release of catecholamines from neuronal extragranular pools.


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