oa South African Medical Journal - The possible central stimulant mechanisms of some appetite suppressants

Volume 46, Issue 4
  • ISSN : 0256-9574
  • E-ISSN: 2078-5135



The probable mechanisms involved in the central stimulating action, as measured by an increase ion locomotor activity of animals, were investigated for a number of phenylethylamine derivatives. Amphetamine, methylamphetamine, propylhexedrine, phentermine, mephentermine and p-chloroamphetamine probably produce their stimulant action by a release of catecholamines from neuronal extragranular pools.

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