oa South African Medical Journal - Epilepsy and IgA deficiency - the effect of sodium valproate

Volume 52, Issue 16
  • ISSN : 0256-9574
  • E-ISSN: 2078-5135



IgA deficiency (<80 IU/ml serum) occurred in 29% of 41 epileptic patients on anticonvulsant therapy. Sodium valproate users had significantly lower mean IgA levels (102 IU/ml) than non-users (151 IU/ml) and had a significantly higher incidence of IgA deficiency (50%) than nonusers (16%).

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