oa South African Medical Journal - Ultrastructure of duodenal epithelial cells in patients with active duodenal ulcers and after treatment with cimetidine

Volume 52, Issue 27
  • ISSN : 0256-9574
  • E-ISSN: 2078-5135



Comparative ultrastructural studies were conducted on biopsy specimens taken under direct vision by endoscopy from the normal duodenum, from the edge of deep and flat duodenal ulcers, and from areas 1 cm away from such ulcers. In addition, the ultrastructure of biopsy tissue from the scar of ulcers which healed after 6 weeks' therapy with the histamine H2 receptor antagonist cimetidine (Tagamet; SKF) was studied.

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