oa South African Medical Journal - Effects of ascorbate on leucocytes - Part IV. Increased neutrophil function and clinical improvement after oral ascorbate in 2 patients with chronic granulomatous disease

Volume 56, Issue 12
  • ISSN : 0256-9574
  • E-ISSN: 2078-5135



A brother and sister with chronic granulomatous disease (CGD) of the autosomal recessive type, and with markedly defective neutrophil motility and elevated serum IgE levels, were treated with a single oral daily dose of 1g ascorbate for 6 months.

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