oa South African Medical Journal - Administration of depolarizing muscle relaxants after non-depolarizer reversal: when is it safe?

Volume 61, Issue 16
  • ISSN : 0256-9574
  • E-ISSN: 2078-5135



In the light of studies on the duration of action and pharmacokinetics of intravenous neostigmine, it is recommended that, depending upon the dosage administered! at least 1 hour should elapse before a depolarizer can safely be given after neuromuscular reversal with neostigmine, and at least 90 - 120 minutes after reversal with physostigmine.

Loading full text...

Full text loading...


Article metrics loading...


This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error