n South African Gastroenterology Review - Hepatitis C virus infection : review
|Article Title||Hepatitis C virus infection : review|
|© Publisher:||In House Publications|
|Journal||South African Gastroenterology Review|
|Author||Johan F. Botha|
|Publication Date||Nov 2003|
|Pages||4 - 7|
Extracted from text ... REVIEW The South African Gastroenterology Review - November 2003 4 Hepatitis C virus infection subtypes with sequence homology of 77 - 80 %.5 Certain genotypes predominate in certain geographic areas and genotype 5 is found almost exclusively in South Africa. Genotype predicts responsiveness to antiviral therapy6 and it is more difficult to achieve a sustained viral response in patients with genotype 1 than in those with genotypes 2 and 3. Preliminary data suggest that genotype 5 is also less responsive to anti-viral therapy. Quasispecies are closely related yet heterogenous sequences of the HCV genome within an infected individual. 7 ..
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