n South African Gastroenterology Review - Plummer-Vinson Syndrome an unusual cause of Dysphagia in the 21st Century : a case report : review

Volume 11, Issue 2
  • ISSN : 1812-1659



Plummer-Vinson or Paterson Brown-Kelly syndrome presents as a classical triad of iron deficiency anaemia, dysphagia and oesophageal web or webs. It is a rare clinical entity in current medical practice with unclear aetiopathogenesis. These patients have a high risk of developing cancer of the hypo-pharynx and upper oesophagus. The response by these patients to iron supplementation and dilatation therapy is remarkable with an excellent prognosis. It is recommended that these patients are enrolled into a regular surveillance upper gastrointestinal endoscopy program for early detection of cancers in the hypo-pharynx and upper oesophagus. We report a case of this syndrome in a 44year old female with intermittent and long standing dysphagia. Investigation revealed iron deficiency anaemia with severe iron depleted state and oesophageal web on oesophagogram. She was treated successfully with iron supplementation and oesophageal dilatation. She is currently on a scheduled clinic follow up in our unit.

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