n South African Gastroenterology Review - Management of refractory gastro-oesophageal reflux : review




Gastro-oesophageal Reflux Disease (GORD) is a common disorder associated with significant impairment in quality of life. The Montreal definition states that it is a condition which develops when reflux of stomach contents causes troublesome symptoms and/or complications. It is estimated that 25-40% of healthy Americans experience the symptoms of GORD at least once a month and that 7-10% of Americans get daily symptoms. Worldwide, the prevalence of GORD is increasing and this is thought to be associated with increasing obesity.


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