n South African Gastroenterology Review - Comparison of efficacy and safety of aluminium-free paediatric alginate and placebo in infants with recurrent gastro-oesophageal reflux : study summary




Gastroesophageal reflux (GOR) is common among infants and young children. It is characterised by vomiting of small quantities of feed during or immediately after feeding. Although the majority of cases (more than 95%) resolve by 18 months of age, persistent vomiting may be associated with significant distress and anxiety for both the child and parents. In addition to relieving distress, treatment may also be important to prevent potential complications, including weight loss and oesophagitis. Management options include postural changes and thickening of the milk mixture.


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