n South African Gastroenterology Review - Abstracts - SAGES Congress 2006 : 5 - 9 August 2006, Feather Market Centre, Port Elizabeth : abstracts

Volume 4, Issue 2
  • ISSN : 1812-1659



Extracted from text ... The South African Gastroenterology Review ? August 2006 34 ABSTRACTS ANALYSIS OF THE FUNCTIONAL 5-HTT POLYMORPHISM IN PATIENTS WITH GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD) R Schroder, MJ Kotze, JNP de Villiers, C Daniels, C van Rensburg Background: Gastro-oesophageal reflux disease effects up to 40% of the general population and can be the cause of strictures, Barrett's metaplasia and cancer of the oesophagus and have a negative impact on quality of life. The role of serotonin is well known in bowel motility and functional bowel disorders. Objective: To determine the potential impact of a functional polymorphism (5-HTT genelinked polymorphic region, 5-HTTLPR) in ..

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